In this study we examined prepotent motor inhibition and responsiveness to reward using a variation of the stop signal reaction time (SSRT) task in clinic- and community-recruited children ages 7 to 12 with attention-deficit/hyperactivity disorder-inattentive type (ADHD-I), ADHD-combined type (ADHD-C), and non-ADHD controls. Contrary to…

Background: Bloodstein reviewed hundreds of studies that investigated the efficacy of therapeutic protocols for ameliorating the stuttering syndrome. Surprisingly, almost all were effective in significantly reducing overtly perceptible behaviours such as repetitions and prolongations of speech sounds. These results seem highly improbable…

Review of neurochemical investigations in autistic disorder revealed that a wide array of transmitter systems have been studied, including serotonin, dopamine, norepinephrine, acetylcholine, oxytocin, endogenous opioids, cortisol, glutamate, and gamma-aminobutyric acid (GABA). These studies have been complicated by the fact that autism is a very…

Gray matter volumes of Heschl's gyrus (HG), planum temporale (PT), pars triangularis (PTR), and pars opercularis were measured on MRI in 48 healthy right-handers. There was the expected leftward PT asymmetry in 70.8%, and leftward PTR asymmetry in 64.6% of the sample. When asymmetry patterns within individuals were examined, there was not one…

Neurological research has demonstrated that brain activity in animals originally dedicated to the production and regulation of physical activity can be decoupled from that physical activity. Furthermore, animals can use the brain activity in this new condition to achieve particular results such as moving a cursor on a screen. These findings are…

A common denominator for the induction of morphological and functional plasticity in cultured hippocampal neurons involves the activation of excitatory synapses. We now demonstrate massive morphological plasticity in mature cultured hippocampal neurons caused by a brief exposure to glutamate. This plasticity involves a slow, 70%-80% increase in…

One-third of the population of US children is considered obese and two-thirds of the adult population falls into the same category. These figures have tripled over the last 30 years. This demonstrates that the existing strategies to combat obesity do not work and it is time to look for alternatives. The recommendation is to turn the problem into a…

A survey of eight levels of neural modelling, coupled with an extensive bibliography, is presented. (Author/HB)

Article presents a theory of the organization of living systems as autonomous entities, and a theory of the organization of the nervous system as a closed network of interacting neurons structurally coupled to the living system to whose realization it contributes. (Author)

THE PROBLEM IS INTRODUCED IN ITS HISTORICAL BACKGROUND. THE SUBSTRATA-FACTOR THEORY IS PRESENTED WITH ITS STATISTICAL MODEL, ITS ASSUMPTIONS, AND THEIR RATIONALE. A CRITICISM OF THE LAST STEP IN SUBSTRATA ANALYSIS IS ENTERTAINED, REJECTED AS IRRELEVANT, AND, THEREFORE, INVALID BECAUSE EXPLANATIONS OF THE CAUSE OR CAUSES OF A CORRELATION MUST…

Auditory evoked responses (AERs) were recorded for 16 autistic children (ages 2-10 years) and age matched normal and retarded controls. The pattern characterizing the effects on AERs of coupling sound and light (conditioning phenomenon) was observed for both autistic and normal controls, but not for retarded children. (Author/DB)

In response to M. Rawson's paper, the author uses an analogy with coronary artery disease to show that current brain research is not entirely at odds with the position that dyslexia may be a developmental variation, rather than a defect. (Author/DB)

Fourteen right-handed stutterers and 14 normal speakers responded to monaurally presented stimuli with their right and left hands. Results suggested a bilateral model of neurolinguistic organization for stutterers in which both hemispheres must participate simultaneously in the decoding process. (Author/DB)

The article discusses types of teratogenic agents, (behavioral defects caused by toxic agents) behavioral targets, organismic vulnerability during growth spurts, teratogenic "routing" (path to the brain), exposure, and duration of effects. Lead is used as a paradigm of chemical neurotoxins known to affect cognitive and noncognitive…