The case study approach provides students with a better appreciation of how scientists solve problems and conduct themselves in the "real world". When applied to the undergraduate chemistry laboratory, this approach also challenges critical thinking skills and creativity in ways "cook book" experiments very often do not. This…

Drug design and development requires collaboration among scientists with diverse expertise. In early-stage drug design, establishment of promising drug candidates requires integration of structure-based molecular design with biopharmaceutics and ADMET (absorption, distribution, metabolism, excretion, and toxicity) principles. Much of this work is…

Visualization of three-dimensional (3D) elements has always played a huge role in chemistry education. At the same time, it is a challenge to teach with most representations being shown in two-dimensional (2D) media. With the recent rise of extended reality (XR) that includes virtual and augmented reality (VR/AR) technology in higher education,…

This study investigates the role of representational competence in student responses to an assessment of hydrogen bonding. The assessment couples the use of a multiple-select item ("Choose all that apply") with an open-ended item to allow for an examination of students' cognitive processes as they relate to the assignment of hydrogen…

Activation energies form an energy barrier to a chemical reaction taking place. Simple collision theory, i.e. that particles need to collide to react, would suggest that activation energy is the energy needed to overcome a coulombic barrier provided by the negatively charged electrons contained within energy shells surrounding an atomic nucleus.…

The themes discussed in this study relate to how students reason about the information encoded in rate constants, which is important for developing a deep understanding of chemical kinetics at the molecular level. This study is part of a larger project centered more generally on students' understanding and use of mathematics in chemical kinetics.…

The aim of this study was to investigate the visual images of pre-service teachers who take biology courses in undergraduate education about biology by analyzing their drawings. The research was conducted with 97 pre-service teachers, studying at the education faculty of a university in Turkey and taking biology course during undergraduate…

Strategies for teaching NMR spectral interpretation in the undergraduate organic chemistry curriculum are often faculty-centered and can lead to student reliance on rote memorization and "guess and check" methods rather than critical-thinking skills for structure determination. This article describes a student-focused methodology for the…

The Franck-Condon Principle (FCP), the key concept for describing vibronic spectra, results from the large disparity between the time scales of electrons and nuclei in molecules. Yet in an undergraduate lecture, the FCP is nearly always rationalized from a time independent quantum mechanical viewpoint, due to students' lack of knowledge of time…

Classroom response systems are an important tool in many active learning pedagogies. They support real-time feedback on student learning and promote student engagement, even in large classrooms, by allowing instructors to solicit an answer to a question from all students and show the results. Existing classroom response systems are general purpose…

The goal of this research is to provide a rich set of connections between two fields: (i) Nanoscale science and technology (NST) and (ii) topics from a common middle school physics curriculum. NST is emerging as one of the most promising new fields of the 21st century, which is one of the many arguments for including NST topics in secondary…

Here we present a new undergraduate laboratory that will introduce the concepts of time-resolved spectroscopy and provide insight into the natural time scales on which chemical dynamics occur through direct measurement. A quantitative treatment of the acquired data will provide a deeper understanding of the role of quantum mechanics and various…

The solving of problems in biochemistry often uses concepts from multiple disciplines such as chemistry and biology. Chemical identity (CI) is a foundational concept in the field of chemistry, and the knowledge, thinking, and practices associated with CI are used to answer the following questions: "What is this substance?" and "How…

The medial prefrontal cortex (mPFC) plays a critical role in complex brain functions including decision-making, integration of emotional, and cognitive aspects in memory processing and memory consolidation. Because relatively little is known about the molecular mechanisms underlying its development, we quantified rat mPFC basal expression levels…

A systems thinking approach to incorporating green chemistry and safety into laboratory culture is vital, as chemists will be at the molecular level of the innovative solutions to our global challenges. Training chemists to have the skills and culture to accomplish this feat in the safest way possible is pivotal to safe working conditions within…