Background: Episodic memory deficits are a characteristic of cognitive dysfunction in people with Down syndrome (DS). However, less is known about the processes (i.e. encoding, retention or using learned information flexibly) that underlie these deficits. Method: We explored these abilities by administering a relational memory and inference task…

N-methyl-D-aspartate receptors (NMDARs) at excitatory synapses are central to activity-dependent synaptic plasticity and learning and memory. NMDARs act as ionotropic and metabotropic receptors by elevating postsynaptic calcium concentrations and by direct intracellular protein signaling. In the forebrain, these properties are controlled largely…

Spatial navigation depends on the hippocampal function, but also requires bidirectional interactions between the hippocampus (HPC) and the prefrontal cortex (PFC). The cross-regional communication is typically regulated by critical nodes of a distributed brain network. The thalamic nucleus reuniens (RE) is reciprocally connected to both HPC and…

Episodic memories in early childhood are rapidly forgotten, a phenomenon that is associated with "infantile amnesia," the inability of adults to remember early-life experiences. We recently showed that early aversive contextual memory in infant rats, which is in fact rapidly forgotten, is actually not lost, as reminders presented later…

Schacter's (2001) work on "The Seven Sins of Memory" conceptualized and communicated many of the failures of memory and their critical role in cognition. At the heart of the framework is the idea that memory often fails not because it is dysfunctional or maladaptive, but because it prioritizes flexibility and the ability to think and…

Aquatic motor activity (AMA) has been reported to affect motor and cognitive abilities. However, the neural mechanisms that may mediate this relationship have never been explored. The traditional functions of the cerebellum include involvement in coordination and balance. Recent studies have shown cerebellar activity during verbal working memory…

Executive functions (EFs) are key abilities that allow us to control our thoughts and actions. Research suggests that two EFs, inhibitory control (IC) and working memory (WM), emerge around 9 months. Little is known about IC earlier in infancy and whether basic attentional processes form the "building blocks" of emerging IC. These…

Practice tests provide large mnemonic benefits over restudying, but learners judge practice tests as less effective than restudying. Consequently, learners infrequently utilize testing when controlling their study and often choose to be tested only on well-learned items. In 5 experiments, we examined whether learners' choices about testing and…

Purpose: Based on evidence of deficits in domain-general cognitive abilities associated with developmental language disorder (DLD), the current study examined sustained attention performance in children with DLD compared to children with typical language development (TLD) and the interrelations between visual-spatial sustained attention,…

This article describes "seductive details" as attention-grabbing, irrelevant pieces of information. They can be words, illustrations, photographs, animations, narrations, videos, or sounds. Studying the effects of seductive details is a growing area of research--but it is far enough along to merit teachers' interest: there are over 20…

According to dual-process theory, recognition memory performance draws upon two processes, familiarity and recollection. The relative contribution to recognition memory are commonly distinguished in humans by analyzing receiver-operating-characteristics (ROC) curves; analogous methods are more complex and very rare in animals but fast familiarity…

This paper argues that educational communities of faith and learning (e.g. Catholic colleges and universities) are especially primed to face into the pain and reality of the sex abuse crisis in honest and constructive ways. Citing the need for strategic collaboration between mental health professionals and religious educators, it calls for…

Infants born low birth weight (LBW) and preterm were evaluated in a high-risk follow-up clinic and compared with infants born full term. A multivariate linear model was used to examine the overall differences on Bayley Scales of Infant Toddler Development (BSID-III) among three groups: full term, heavy LBW (<2,500 g [greater than or equal to]…

Existing affect scales typically involve recognition of emotions from a predetermined emotion checklist. However, a recognition-based checklist may fail to capture sufficient breadth and specificity of an individual's recalled emotional experiences and may therefore miss emotions that frequently come to mind. More generally, how do recalled…

This study examines the long-term retention of anatomical knowledge from 180 students after various repetition activities. The retention of anatomical knowledge was assessed by multiple-choice tests at five different points in time: before and after a course in Functional Anatomy, before and after repetition activities that occurred 14 weeks after…