Students who are seriously academically deficient, those who are underprepared in all subjects, face many academic challenges as they begin their coursework in higher education. However, students also face nonacademic and personal issues that create additional barriers to success. The results of this study suggest that increases in student success and retention may be achieved if developmental educators also address nonacademic and personal factors related to student success: (a) clear student guidelines, (b) integrating first-year transition coursework, (c) intrusive academic advising to treat the nonacademic and personal factors, and (d) traditional developmental education coursework and tutoring to address academic factors. The increase in the mean grade point average of Pathways to Success Program students as compared to nonprogram students, from 1.503 to 2.151, was statistically significant (p = 0.000). Increases in the number of students in good academic standing, increases in success in developmental education courses, and increases in the 1-year retention rate were also noted for participating students. (Contains 5 tables.)