What can CBT therapists do when interpersonal issues are pertinent to therapeutic change and there is a deficit of CBT literature offering clinicians' guidance on how to address this as part of the therapy process? Do we say "clients are resistant?", "Not ready for change?", or "there is too much secondary gain?" As therapists we may not be familiar with taking personal responsibility for looking at how our own processes also affect the therapeutic journey with our clients. Recent advances suggest that focusing on the process rather than the content in moderate to severe depression is effective and also consistent with the "Third Wave" of CBT as it evolves. The debate about the efficacy of challenging thoughts has also been raised (Longmore & Worrell, 2007). This case study presents the analysis and treatment of depression following the formulation and treatment of Behavioural Activation (BA) and Functional Analytic Psychotherapy (FAP). It is within the context of interpersonal issues arising during BA treatment of depression. FAP uses the therapeutic relationship as a vehicle to promote natural reinforcement and generalisation into the client's daily life based upon functional analysis, radical behaviourism and intimacy. (Contains 2 tables.)