PowerPoint[R] presentations in academia have a reputation for being less than engaging in this era of learner-centered teaching. The Net Generation also presents a formidable challenge to using PowerPoint[R]. Although the research on the basic elements is rather sparse, the multimedia elements of movement, music, and videos have a stronger evidence base and have the potential to increase learning. That research will be briefly reviewed. Since the use of multimedia as instructional tools has been largely ignored by the major sources on PowerPoint[R], this article presents 30 specific practical applications enabling faculty members to improve the effectiveness of their PowerPoint[R] presentations and to grab and maintain students' attention and foster deep learning.