Secondary school administrators are increasingly finding themselves in the position of implementing Response to Intervention (RTI). This system of providing progressively intensive levels of intervention for the purposes of preventing academic failure and identifying children with learning disability may be useful at the secondary level. However, many aspects of RTI are based on research conducted in elementary schools. The purpose of this article is to provide a basic description of RTI, to summarize research conducted at the secondary level, and to provide a set of considerations for secondary administrators regarding RTI implementation.