In this digital age, is primary science being left behind? Computer microscopes provide opportunities to transform science lessons into highly exciting learning experiences and to shift enquiry and discovery back into the hands of the children. A class of 5- and 6-year-olds was just one group of children involved in the Digitally Resourced Engaging And Motivating Science (DREAMS) project, funded by the AstraZeneca Science Teaching Trust. The project involved six primary schools from across Northern Ireland working with science advisers and tutors from Stranmillis University College Belfast to develop their use of digital resources within cross-curricular science. In this article, the authors focus on how the recently introduced TTS Easi-Scope can be used alongside the more established Digital Blue QX5 computer microscope to support exciting and inspiring cross-curricular science lessons. They compare computer microscopes and their ability to enhance science enquiry. (Contains 4 figures.)