It has been over twenty years since the publication of reports calling for increased efforts to reform undergraduate STEM (science, technology, engineering, and mathematics) education. There are more STEM classrooms today that utilize "pedagogies of engagement" than there were twenty years ago; however, these kinds of learning environments are still not as common as they should be given the overwhelming evidence of their positive outcomes. Project Kaleidoscope (PKAL), because of its track record in highlighting and addressing issues in STEM higher education and its new partnership with the Association of American Colleges and Universities (AAC&U), is uniquely situated as a national, cross-disciplinary, undergraduate STEM education organization to address these challenges. Since its founding in 1989, PKAL has been pushing the frontiers of innovation in STEM pedagogy and faculty development, leadership capacity building, and network creation among its cross-disciplinary membership. As PKAL formulates its next-generation agenda, it does so within the context of a new formal partnership with AAC&U. In January 2010, PKAL formally joined forces with AAC&U to advance and amplify the work of both organizations with respect to transforming undergraduate STEM learning, teaching, and leadership. With AAC&U as an active partner, PKAL now has even greater potential to expand the number of faculty, administrators, and institutions involved in its programs and networks. PKAL is committed to working within existing and new AAC&U programs on general education and assessment, global learning, public health, and inclusive excellence in order to deepen the attention paid to STEM learning. (Contains 2 figures.)