Faculty and researchers who receive substantial funding from NIH were interviewed about their publication practices. Qualitative data was collected from interviews of eleven faculty members and one researcher representing six academic departments who received NIH funding. Interview responses were analyzed to identify a representative publication workflow and common themes related to the publication process. The goals of this study were to inform librarians about faculty publication practices; to learn how faculty are affected by and responding to NIH publication policy changes; and to inform planning and discussion about new services to support NIH compliance in addition to general faculty publishing. Major themes from the interviews included consistency in publishing workflows, but variety in authorship patterns and in data management practices. Significant points of pain for authors included difficulty finding quality reviewers, frustrating submission processes, and discomfort about the implications of publication agreements. Some authors found the NIH submission requirement to be burdensome, but most assumed their publishers were taking care of this process for them. Implications for library services are considered. (Contains 2 tables and 1 figure.)