If spirituality is, among other things, a matter of "connectedness", then how do we nurture spirituality in adolescents with developmental disabilities who seem largely disconnected? This article advocates the practice of friendship as one important Christian model of spiritual connectedness that finds its origins in the initiative of God and addresses the fundamental human experience of loneliness and fear of negation. I argue that by participating together with adolescents with developmental disabilities in Christian practices, especially the practice of friendship, we open up spaces where their spirituality and ours will be nurtured. (Contains 5 notes.)