Higher education institutions are confronted with increasing demand for electronic access to educational opportunities, improved academic quality and accountability, and new academic programs that address societal workforce and economic development needs. Collaboration allows institutions to combine resources to respond efficiently and effectively to these demands. In this article, the authors make a cogent case for multi-institutional collaboration, outlining the many benefits of online academic programs, criteria for collaborative programs, partner selection process, curriculum development, financial agreements, alliance management, communication, and conflict resolution. They conclude with a case study of a successful engineering consortium.