This article explores the potential for introducing harm reduction into sexuality education. When the goal of sexuality education is on prevention and focuses on risk and public health concerns, a discussion of pleasure is rendered problematic, as many pleasurable behaviors are inherently "unsafe" or "risky" when considered using a safe-sex lens. The authors argue that integrating harm reduction into a national strategy to enhance sexual health will provide participants in sexuality education programs the agency to make educated harm-aware choices about their behavior. A harm reduction paradigm offers an opportunity to negotiate pleasure "and" safety in a paradigm that juxtaposes "unbound pleasure" and "restricted sexual safety," rather than one that allows for either unsafe or safe sexual behavior choices.