This article presents a short case presentation and differential diagnosis of impetigo, a common, contagious, superficial skin infection that is produced by streptococci, staphylococci, or a combination of both bacteria. There are two different clinical presentations: (1) bullous impetigo; and (2) nonbullous impetigo. For years, it was thought that bullous impetigo was caused by "Staphylococcus aureus" whereas nonbullous impetigo was primarily a streptococcal disease. It is now known that "S. aureus" is the primary pathogen of both types of impetigo. Impetigo is usually considered a mild disease, but complications are not uncommon. The author provides a discussion of impetigo and how a school nurse should handle it. (Contains 2 figures.)