Universal Design for Instruction (UDI), a construct that serves as the foundation for the work of a federally funded project at the University of Connecticut, offers an approach to inclusive instruction that is responsive to the diverse learning needs of a changing postsecondary population. In this article elements relating to the implementation of project activities are presented, including the participation of key stakeholders throughout the grant period. The application of the Nine Principles of UDI[C]to college teaching is discussed along with observations regarding project outcomes. Suggestions for future initiatives are also delineated. (Contains 1 table and 1 endnote.)