Research on whether health education, specifically personal health classes affects behavior change is inconclusive. In this study, a sample of students from two large southeastern universities enrolled in a required personal health course and an elective personal health course were administered the National College Health Risk Behavior Survey (NCHRBS) and the Self-Efficacy Scale. These surveys provided information on the overall health risk behaviors, health behavior changes, and self-efficacy levels of the student participants. Significant proportional differences were found within the descriptive and multiple regression analyses of (a) riding in a vehicle with a driver who has been drinking alcohol, (b) tobacco use, and (c) dietary behaviors. However, the small effect sizes indicated that the differences between the two schools were not large. Significant differences were also found among the comparisons of the current survey results to the national survey results collected by the Centers for Disease Control and Prevention in 1995. Further research is needed to determine how generalizable these findings are. (Contains 2 tables.)