Applying a qualitative research design and using questionnaires, interviews, observation, focus groups, and debate, this study examines the phenomena and implications of change on LIS curricula, the stakeholders' perception of the current curriculum, the processes of curriculum design and review, and the impact of social, economic, political and technological factors at the East African School of Library and Information Science (EASLIS). For comparative purposes, experiences in the Departments of Library and Information Studies at the University of Wales (Aberystwyth), Botswana and Cape Town are also examined. Findings suggest the need for curricula policy, improvement of programme content both in academic and ICT aspects, indigenisation and harmonisation of programmes, the adoption of varied teaching methods, improvement of space, teaching, research and ICT facilities, internalisation of programmes and the introduction of a practicum are required at EASLIS.