The effects of at least 23-hr deprivation, 5-min presession exposure, and individual preference on the acquisition of mands were investigated in these studies. Two boys who were 2.5 years old and diagnosed with autism participated in the studies. Preference assessments were conducted to identify preference levels of various toys. Toys of various preferences were then assigned to either a 23-hr deprivation or 5-min presession exposure condition for mand training. Both deprivation and preference level affected acquisition of mands. Implications for teaching children to mand are discussed. (Contains 4 figures.)