That two-thirds of depressed adults are resistant to medication has led to the addition of psychotherapy to treatment, but is medication necessary? Results are at least as good with psychotherapy alone, and the relapse rate is less. Handling of suicidal danger, sleep disorders, and common depressing issues in college students are discussed along with the successful psychotherapies of a suicidal depressed 25 year old and a recurrent psychotic depression in an older man who should have received psychotherapy when he was 20.