Introduction: This study consisted of a qualitative investigation into the role of e-mail in work-related burnout among high technology employees working full time and on-site for Internet, hardware, and software companies. Method: Grounded theory methodology was used to provide a systemic approach in categorising, sorting, and analysing data gathered in semi-structured interviews with seventeen high technology workers. Analysis: Data were analysed following the grounded theory principles: open coding and memos for conceptual labelling, axial coding and memos for category building, and selective coding for model building. Results: The end result of the grounded theory process was a theoretical model showing that e-mail misuse and overuse in the context of a fluid, fast-paced, and constantly changing environment, such as the high technology industry, start a chain of events that contributes to prolonged work-related stress or burnout. Conclusion: This study is intended to create awareness of the risks of e-mail becoming an obstacle to productivity and workers' well-being. This awareness allows organisations and individuals to engage in more constructive practices regarding e-mail to the benefit of their social actions and interactions both inside and outside their workplaces. (Contains 1 figure and 1 table.)