This paper describes the interoperability underpinning a new strategy for delivering accessible computer-based resources to individual learners based on their specified needs and preferences in the circumstances in which they are operating. The new accessibility strategy, known as "AccessForAll," augments the model of universal accessibility of resources by engaging automated systems and builds upon the previous development of libraries of suitable resources and components. It focuses on individual learners and their particular accessibility needs and preferences. It fits within an inclusive framework for educational accommodation that supports accessibility, mobility, cultural, language and location appropriateness and increases educational flexibility. Its effectiveness will depend upon widespread use that will exploit the "network effect" to increase the content available for accessibility and distribute the responsibility for the availability of accessible resources across the globe. Widespread use will depend upon the interoperability of "AccessForAll" implementations that, in turn, will depend on the success of the four major aspects of their interoperability: structure, syntax, semantics and systemic adoption. (Contains 1 figure.)