This article describes one school's effort to establish a social work research development center in the area of coexisting drug and mental disorders (dual disorders), within the context of the social work profession's efforts to compete more effectively for federal research grants. This center was funded as part of a successful application in response to the National Institute on Drug Abuse's announcement of support for a Social Work Research Development Program stressing the development of social work research in drug abuse intervention and services research. The center builds on the school's previous research and training experiences in the area of co-occurring drug and mental disorders. The center's purpose, structure, and institutional impact are described, with particular attention to the challenges faced in both its formation and its operation and the lessons learned that could generalize to other similar efforts.