This article describes the design features of a mentoring program that evolved from a university/school system partnership. Findings from participant interviews suggest key issues to be considered in designing and implementing a school systemwide mentoring program such as recruitment of mentor teachers, incentives for mentor teachers, release time for mentors and new teachers for observing and conferring, and obtaining and retaining both building-level and systemwide support. Suggestions are given for key elements to consider in designing a research-based mentoring program that addresses the needs of new teachers. The study also describes what can be accomplished when school systems and institutions of higher education pool their resources and set common goals. (Contains 2 notes.)