This paper examines research into teaching, learning and assessment (TLA) in higher education in terms of structure and agency. It argues that although issues of structure and agency are seen as crucial in social theory, they are very little discussed in research into TLA in higher education and that a consideration of structure and agency raises some important questions about this research and the quality of the explanations that it generates. It is therefore time to reconsider this research from the standpoint of structure and agency so that more sophisticated approaches to researching, and generating explanations of, teaching, learning and assessment in higher education can be developed.