Child- and family-serving programs such as the Special Supplemental Nutrition program for Women, Infants, and Children (WIC) design and conduct interventions to improve the health of their clients through better nutrition. But these programs present a significant opportunity to improve physical activity levels in the preschool population as well, and professionals in health and physical education are in a unique position to work with these programs to promote a healthy and active lifestyle among children. This article gives some background material and recommendations for collaborating with WIC programs to improve the health and physical fitness of at-risk children with few resources.