Social work has traversed a vast expanse since its roots in settlement houses and as friendly visitors to making a profound mark on the world of social science research. The authors begin by examining the role of research in the social work profession and then discuss current changes, directions, and challenges in the pursuit of research funds. Highlighted will be Career Development Awards, specifically the Mentored Research Scientist Development Award or the K01 mechanism offered by the National Institutes of Health. A historical context is set, the mechanism described, and two social work K01 grantees illustrate the utility and promise of this funding source for conducting social work research. This manuscript aims to help readers determine (a) if the K mechanism is a good fit with their goals and needs and (b) how to pursue a K-Award successfully. (Contains 1 table and 1 note.)