Although evidence-based practice (EBP) has received increasing attention in social work in the past few years, there has been limited success in moving from academic discussion to engaging social workers in the process of implementing EBP in practice. This article describes the challenges, successes, and future aims in the process of developing a university-based institute for evidence-based social work. Aspects of the development include attempting to address concerns and critiques through developing an inclusive model of EBP; engaging community agency partners as active participants in the process; developing collaborative research projects with community partners to further the research evidence available for practice; conducting systematic reviews; finding means of disseminating review and research findings broadly in order to effect social policy revisions and lead to the development of effective programs and practices; and training agency personnel and social work students in the process of EBP and conducting practice evaluation research. (Contains 1 figure.)