Background: This paper describes a portion of a larger evaluation project of a state hepatitis prevention program. Purpose: The study explored the suggestions of key informants related to the delivery of hepatitis services in the state. Methods: Researchers conducted key informant interviews lasting 30 to 45 minutes. Results: Important findings included: (1) administrative support of the hepatitis program was critical to staff perception of its importance; (2) outreach and public education as well as marketing were seen as important components of the program; (3) continued resources and investments in staff training and development were important to creating a supportive environment for staff and clients and providing for program institutionalization. Discussion: Staff education concerning the program's mandate, expectations, and outcome measures would aid in the institutionalization process. The addition of interorganizational support from partner agencies that can provide access to high-risk populations and treatment will facilitate further institutionalization of the state hepatitis program within the individual counties. Translation to Health Education Practice: Specific findings that fit with health education practice are (1) outreach and public education should be expanded, and (2) senior administrative support for the hepatitis program is critical to its success. (Contains 1 figure.)