After forty-nine years of watching and working in higher education, Arthur Chickering has determined that three R's truly are fundamental to helping students learn. In stark contrast to the traditional set, Chickering's three R's challenge educators to recognize, respect, and respond to wide-ranging individual differences among diverse learners. The suggestions in this article for recognizing, respecting, and responding to individual differences among students are highly synergistic. When each initiative is seen as part of a larger strategy, the cohesion and integration that results sharply increases the likelihood that all students will learn. Most important, the institutional culture will be characterized by the three R's. (Contains 2 notes.)