There is a predicted increase in the number of children with HIV/AIDS in schools. Due to this increase, schools and educators need to be prepared for the special needs these children may have. In the present aggregate of literature and research, the following topical strands are examined: (a) overview of HIV/AIDS in school children; (b) HIV/AIDS demographics and incidence; (c) legal issues; (d) medical and psychosocial issues; (e) special education issues; (f) biases and barriers; (g) school policies, knowledge base, and training level; and (h) implications for practice.