Fifty-two mother-adolescent dyads (mean adolescent age = 16.3) participated in an observational study of communication about health topics. The aim of the study was to examine mother-adolescent conversations about health issues--drugs/alcohol, sexuality, nutrition/exercise--to determine the extent to which the mothers treat these issues similarly. Across conversations, mothers spent more time asking questions than lecturing or discussing negative consequences. Mothers discussed negative consequences less in the nutrition/exercise and sexuality conversations than in the drug/alcohol conversation. Mothers asked fewer questions when discussing nutrition/exercise than drugs/alcohol, and lectured more in the nutrition/exercise conversation than in the sexuality conversation. The results of this study have implications for intervention programmers advocating in the media that parents "talk to your kids" about these health issues.