Objective: The authors examined the influence of a holistic model of wellness on activity level among obese and sedentary college students. Participants: They recruited 41 participants for an 11-week program. Methods: Participants were required to record daily walking totals and complete 5 bimonthly classes where principles of holistic wellness were discussed. Pre- and posttest values of activity level (walking activity, cardiovascular training, general activity, and resistance training) and pre- and posttest knowledge and self-efficacy related to principles of holistic wellness. Participants also completed a 1-month followup. Results: Participants who completed the program reported increases in general exercise activity, resistance training, and walking behavior, as well as self-efficacy and knowledge concerning principles of holistic wellness. The authors also observed decreases in participants' body fat and body mass. Conclusions: Relevance to adherence of exercise behavior and a lifestyle approach to health are discussed. Future directions and limitations are highlighted. (Contains 4 tables.)