This study investigated the relationship between psychological distress and attitudes toward seeking professional help and whether the relationship was moderated by gender and student status (traditional vs. non-traditional) among Chinese college students in Taiwan. 961 first-year university students completed standardised measures of depression, anxiety, attitudes toward seeking professional psychological help, and a demographic questionnaire. Results from the multiple regression analysis found that while higher levels of depression were adversely correlated with help-seeking attitudes, gender was positively correlated with help-seeking attitudes. Chinese female students held more favourable attitudes toward seeking psychological help than their male counterparts. Additionally, gender interacted with depression and anxiety in affecting attitudes toward help-seeking. These results were discussed within the Chinese cultural context and recommendations were given for student outreach programme aimed at increasing utilisation of mental health services on campus. (Contains 2 tables.)