This paper gives a description of the support needs of people with profound multiple disabilities (PMD), based on the five basic dimensions of the 2002 AAMR System, being intellectual abilities, adaptive behavior, participation, interaction and social roles, health and context. It is based on a study of the literature concerning the target group. The overview shows that people with PMD have the same needs as other people, with regard to participation, relationships, choices, resources and physical and socio-emotional well-being. Nevertheless, it becomes apparent that the needs of people with PMD require specific support. In order to meet these special needs, a relational perspective on support as well as specific characteristics of the support staff and of the support context are necessary. (Contains 1 figure.)