School-wide positive behavior support (SWPBS) has been identified as an effective and efficient method to teach students prosocial skills. It requires both effective behavior support practices and systems that will support these changes, including data-based decision making among the school leadership team. There are many practical and systemic factors that school personnel should examine before they consider themselves ready for systemic school-wide changes, including those associated with the (a) leadership team, (b) staff, (c) administration, (d) coach/facilitator, and (e) district. Practical considerations in each of these areas will be identified and discussed so that practitioners can anticipate their needs as they create effective SWPBS, particularly in low performing urban schools.