Science educators are often among the first to use emerging technologies in the classroom and laboratory. For the technologically savvy science teacher, the handheld computer is a terrific tool. A handheld computer is a portable electronic device that helps organize (via calendars, contact lists, to-do lists) and integrate electronic data (documents, spreadsheets, media, e-mail, companion software) into the mobile lifestyle of busy professionals and many students. Handheld devices have long had the potential for applications in the classroom, but recent advances and affordability in wireless technologies have enhanced their applicability in schools and created opportunities for educators to improve on process and management efficiencies. This article discusses the useful applications of handheld computers in the classroom: (1) streamlining attendance and grading; (2) assessing student work during laboratory exercises; (3) managing cooperative learning; (4) minimizing data synchronization operations; and (5) freeing up time. (Contains 1 figure and 3 resources.)