This is the first study to examine Holland and Gottfredson's [Holland, J. L., & Gottfredson, G. D. (1994). "Career Attitudes and Strategies Inventory: An inventory for understanding adult careers." Odessa, FL: Psychological Assessment Resources.] assertion that the Career Attitudes and Strategies Inventory (CASI) is a useful instrument for differentiating career persisters and career changers. Based on Holland's (1996; Holland and Gottfredson) [Holland, J. L. (1996). Exploring careers with a typology: What we have learned and some new directions. "American Psychologist, 51," 397-406.] expectations and empirical evidence it was hypothesized that persisters (expressed intent to remain in current career) would score higher than changers (expressed intent to change career) on the Job Satisfaction, Work Involvement, Skill Development, and Geographical Barriers scales comprising the CASI. Conversely, it was hypothesized that changers would score higher than persisters on the CASI scales measuring Dominant Style, Career Worries, Interpersonal Abuse, Family Commitment, and Risk-Taking Style. To test these hypotheses, 249 career persisters and 200 career changers completed the CASI. Results indicated that changers were more likely to take risks and were more motivated towards skill development, while persisters were more satisfied in their jobs and reported greater career concerns.