This study investigated the use of practitioner-implemented structural analyses to determine setting events affecting the disruptive behavior of two male students with EBD in a self-contained classroom. Descriptive measures (PBQ, SEII, and direct observation) and analogue probes were employed and contrasted. An ABA reversal design was used to compare intervention packages; maintenance and social validity data were also obtained. Findings indicate that structural analyses can be implemented by a practitioner and can lead to the development of successful interventions within educational settings. Implications for broad implementation and future research are also discussed. (Contains 2 tables and 4 figures.)