Mid-career faculty are the keystone of the academic enterprise. They fill essential instructional, program development, administrative, and citizenship roles at their institutions. They form a bridge between faculty generations by mentoring new colleagues and assuming leadership duties as their senior colleagues move toward retirement. Mid-career faculty are key players as their institutions adapt in a time of continuous change. They can be either allies or stubborn opponents as their institutions adjust to competitive pressures, revise programs to meet the needs of increasingly diverse students, and integrate new educational technologies. This article examines strategies that several progressive higher education institutions are using to support and gain maximum benefit from their mid-career faculty members. (Contains 1 figure.)