We evaluated the influence of child location on the occurrence of self-injurious behavior (SIB) during functional analyses conducted in home settings. An initial functional analysis conducted with 2 children who had developmental disabilities showed undifferentiated patterns of SIB. Analyses of behavior during free play suggested that the child's location was an active variable for self-injury. Both children showed a decrease in self-injury when they were placed next to their parent versus being placed in a wheelchair or on the floor. A second functional analysis was conducted with child and parent on a couch. Results showed low percentages of self-injury during free play, but high percentages during other test conditions. Functional communication training programs for each child resulted in decreases in self-injury.