This paper explores ways to bring together local and global knowledge systems in the context of education. It first discusses the concepts of native science and of intercultural education, key ideas in Ecuadorian indigenous education today. Both of these concepts seek to unite the local and the global in new ways. It explores the views of Ecuadorian indigenous educators and leaders around issues of education and science. The primary need voiced by these individuals is that of defending their communities against various kinds of encroachment, economic as well as cultural, and the enterprise of education is viewed within this reality. Finally, the paper discusses the paradigm of place-conscious education, which the author argues is a unifying conceptual framework that speaks to the concerns voiced by these educators as well as those of educators elsewhere. (Contains 4 notes.)