ERIC Number: EJ735664
Record Type: Journal
Publication Date: 2005-Aug
Pages: 4
Abstractor: Author
ISBN: N/A
ISSN: ISSN-0162-3257
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Available Date: N/A
The Treatment of the Behavioral Sequelae of Autism with Dextromethorphan: A Case Report
Woodard, Cooper; Groden, June; Goodwin, Matthew; Shanower, Cori; Bianco, Joanne
Journal of Autism and Developmental Disorders, v35 n4 p515-518 Aug 2005
Dextromethorphan is the d-isomer of levorphenol, and an ingredient in antitussive preparations. A 10 year-old male diagnosed with Autistic Disorder, Pervasive Developmental Disorder, and Generalized Anxiety Disorder was administered this medication initially to treat a medical condition. This became a quasi-experimental ABAB design (A = baseline, B = treatment), with improvements during treatment phases shown in tracked behavioral data and anecdotal reports. Several candidate mechanisms to explain the improvements are offered, including glutamate receptor antagonism. While dextromethorphan is not commonly administered for the treatment of behavioral challenges in this or any population, the results suggest the need for larger-scale, adequately controlled, and methodologically rigorous studies of the potential clinical effects of dextromethorphan.
Descriptors: Autism, Case Studies, Males, Quasiexperimental Design, Drug Therapy, Behavior Problems, Behavior Change, Outcomes of Treatment
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Publication Type: Journal Articles; Reports - Research
Education Level: N/A
Audience: N/A
Language: English
Sponsor: N/A
Authoring Institution: N/A
Grant or Contract Numbers: N/A
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