The overriding aim of MANOR--a national mathematics teacher center--in the last decade has been to provide a theoretically sound, research-based and practically feasible framework to support Professional Development (PD) for teachers of mathematics at a time of curriculum reform in Israel. This paper focuses on the preparation of, and support for, providers of PD for teachers of mathematics, offered at MANOR. The paper describes various components of MANOR (the MANOR Program, Forum, Conferences, individual support, and Resource Files) after 10 years of activity, situating MANOR in the Israeli context. The paper also elaborates the theoretical orientations on which MANOR draws, with relation to a central characteristic of MANOR, namely, the integration of knowledge and practice in the development of PD providers.