In times of dramatic social change, new career options emerge and old options may become obsolete. We investigated predictors of change in general career aspirations and of plans to attend a university of East German adolescents from 1989 (before German unification) to 1991 and 1995, respectively, after German unification. Higher pre-unification self-efficacy beliefs were associated with an increase in general career aspirations and a higher probability of switching from non-college-bound vocational training to attending a university. In addition, better pre-unification school grades and having parents who graduated from a university increased adolescents' probability to switch to a university. Furthermore, interaction effects of self-efficacy with grades and cognitive abilities appeared, indicating that for individuals with high self-efficacy, cognitive abilities became more important and grades less important in predicting the wish to pursue university studies. We concluded that beliefs in one's capabilities, and high academic abilities are important resources in vocational reorientation in times of social change.