Concurrent and prospective associations between parent-youth dyadic hostility and adolescent externalizing and internalizing problem behavior were examined in a sample of 416 families. Parenting control, parents' well-being, and youths' affiliation with deviant peers were included as integral covariates. Information from multiple sources was analyzed using structural equation modeling. Concurrently, youth externalizing problems were associated with dyadic hostility, deviant peers, inadequate parenting control, and fathers' well-being (inversely). Internalizing problems were associated with inadequate parenting control and lower levels of fathers' well-being. Prospectively, some of these relations continued over 2 years, with a few new associations emerging. A process model is proposed in which parent-youth dyadic hostility during early adolescence influences parenting, peer relations, and parents' well-being over time.