Ten individuals with profound multiple impairments were given novel tests for learning and preference with adaptive switches and leisure-oriented devices, such as audio tape players. Typically, tests for learning include a baseline or extinction component in which the adaptive switch and device are not connected as a control for incidental or involuntary switch use. As an alternative, conditions were compared in sets of six sessions each in which switch closure caused (a) Activation of a device, (b) Deactivation of an already operating device, and (c) Deactivation of one of two devices and Activation of the other (Two-Choice). Changes in behavior indicative of learning were observed in eight participants in Activation-Deactivation conditions. The Two-Choice Condition produced indices of learning that also showed a preference for one device over the other with five participants. The preferences observed in the Two-Choice Condition had not been seen in the Activation or Deactivation Condition data. People with profound multiple impairments evinced leisure-device preferences, but such preferences may not lead to differential responding across opportunities with only one device at a time.