E-mail has never been a foolproof way of sending information. It would make sense to follow-up with a phone call if something crucial is sent to make sure it has arrived. This is particularly true if a large file or files are to be sent by way of an e-mail attachment. ISPs typically limit attachments in received e-mails to 2-10 megabytes, which is not always large enough for presentation, photo, audio, or video files. There are many options to choose from when sending large files, but whatever method is used, it also makes sense to check with the recipients before sending to make sure they have access to the same technology or would not be difficult for them to use. This article presents several suggestions on how to send large files using the latest information technologies.