The mass-casualty school shooting incidents in recent years have heightened concern about the safety of U.S. schools and prompted responses that, in many cases, have centered mainly on bolstering security on school campuses. Some researchers have concluded, however, that the most effective prevention efforts are those that are more comprehensive in scope. This article explores selected spiritual, religious, and family value factors that research has indicated may play an important protective role in strengthening resilience in young people and minimizing at-risk behavior that may be associated with school violence.