This paper explores whether female undergraduates self-reported experiences of pre-menstrual syndrome (PMS) were associated with degree performance, operationalized as degree class outcome, in a sample of 'high achieving' students (N = 55). Students reported that PMS was disruptive to academic work (comprising lectures, seminars, writing essays, reading, examinations and interviews) but no association was found between degree performance and either the number of PMS symptoms reported or the reported disruption to each aspect of academic work.