Analyses of data collected from 480 university students (approximately 56% White and 44% Black) challenge the utility of the Multi-Attitude Suicide Tendency Scale (MAST) for use with individuals of diverse cultural backgrounds. This size sample allowed for an examination of the psychometric properties and cultural relevance of the MAST for non-Whites. Correlations between scores on the MAST, suicide, and depression measures were in the expected directions for Whites but not for Blacks or Latinos. The White sample data fit the four-factor model of the MAST, but the model required several modifications to fit the data from the Black sample. Verification of the cultural relevance of the MAST and a revision of the scale are recommended to improve its usefulness.